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In some cases, the discontinuation of GLP-1 therapy can result in weight regain due to a rebound effect [43, 44]

Dosage and Adjustments Typically starts at 0.25 mg once a week, increasing gradually to minimize side effects

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BMJ: Canada Is Only the Second Country to Clear Generic Semaglutide Advertisement Felix Canada has become only the second country in the world to approve a generic form of semaglutide, the active ingredient in Novo Nordisk's Ozempic, according to a report published in The BMJ on May 19, 2026 [Source: bmj.com/content/393/bmj-2026-597166]