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While passive diffusion was initially proposed as the main absorption route, recent evidence indicates that specific transmembrane transporters including Na-taurocholate cotransporting polypeptide, organic anion-transporting polypeptides, L-type amino acid transporters, and monocarboxylate transporters also facilitate LT4 uptake

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For example, Lucy, a 39-year-old nurse, mentioned experiencing mild discomfort at the injection site, which initially deterred her from continuing the treatment

Wang L, Ahn YJ, Asmis R

For weight-loss evidence context, review Mayo Clinic information on B12 injections and weight loss