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EAAC1 gene expression is promoted by nuclear factor erythroid 2-related factor 2 (Nrf2) [64], regulatory factor X1 (RFX1) [65], and all-trans-retinoic acid (ATRA) [66], while miR-96-5p, which is one of the microRNAs (miRNAs), has a target sequence in the 3-UTR of EAAC1 and suppresses the protein expression of EAAC1 posttranslationally, leading to decreased GSH levels in the brain [67,68] (Figure 3)
Abstract Diet composition shapes tissue function and disease risk by modulating nutrient availability, metabolic state and cellular dynamics 1
GLP-1 signaling also exerts potent anti-inflammatory effects within the central nervous system
In recent years, there has been increased interest in the possible role of orexin-A/hypocretin-1, a neuropeptide hormone implicated in the pathogenesis of narcolepsia, on the development of excessive daytime sleepiness in PD patients
What It Means for Retail & Brand Strategy At JW Sales and Marketing, we help brands make the most of moments like this
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