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The 1,098 participants in AWARD-5 had a mean baseline HbA 1c of 8.1% despite being on metformin and, in one-quarter of cases, an additional oral antidiabetic agent

First, evaluate variables beyond product quality: dose level, administration technique, storage conditions, and dietary compliance

You could extend the maintenance phase or continue titrating to 12mg depending on your response and goals

Butyrate supports the intestinal lining, reduces inflammation, and enhances metabolic function, improving glucose metabolism and insulin sensitivity (Liu et al., 2015)