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Several linear (Manier et al., 2020) and non-linear strategies (QC-Robust Smoothing Splines (QC-RSC) (Kirwan et al., 2013), QC-Support vector regression correction (QC-SVRC)) (Moreno-Torres et al., 2021) have been proposed for the modeling of within-batch effects

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Patients should be encouraged to engage in regular moderate-intensity exercise, starting with short durations (10-15 minutes) if necessary and gradually increasing