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For men carrying significant visceral fat, the transformation in abdominal profile can be dramatic, losing 4 to 6 inches off the waist is common by this point

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These include: Nausea Vomiting Diarrhea Constipation Bloating and abdominal discomfort Gastrointestinal Tolerability and Dose Escalation For both tirzepatide and retatrutide, gastrointestinal symptoms are most pronounced during the initial initiation phase and immediately following a dose escalation step