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Analysts forecast FDA approval around 2027

136 Exogenously administered somatostatin inhibits glucagon release from islet alpha-cells and insulin release from islet beta-cells, and antibodies against somatostatin induce glucagon secretion from islet alpha-cells

This is the first Phase 3 GLP-1-class readout that specifically demonstrates symptomatic benefit in knee osteoarthritis beyond what would be expected from weight loss alone, and it opens the possibility, still to be confirmed in dedicated trials, that GLP-1 receptor signaling has direct anti-inflammatory or disease-modifying effects on joint tissue

Zhong Q, Chen R, Zhang M, Chen W, Chen H, Chen W

Most regenerative medicine requires minimal downtime