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this was shown to protect against Ang II-induced injury in the heart and aorta, potentially associated with inhibition of NOX4 expression and preservation of mitochondrial integrity, reduced the protein levels of NADPH oxidase 4 (NOX4) and TGF1 and expression of monocyte chemoattractant protein 1, and attenuated the proliferation of myofibroblasts culminating in reduced aortic wall thickness [81]

Mingxing Lu, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

When muscle diminishes, skin has even less to hold onto, worsening the appearance of laxity and aging

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10.1016/j.phrs.2023.106766 125 XuS.LiX.LiY.LiX.LvE.ZhangX.et al (2023b)