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Deudextromethorphan (AVP-786), a similar weak NMDA receptor antagonist combination of deuterated dextromethorphan and quinidine, was investigated in a 2016 phase 2 study for treatment of MDD (NCT02153502)

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(60) utilized next generation sequencing (NGS) and computational analysis to demonstrate that miR-23b-3p, acting as a tumor suppressor, can inhibit tumor Gln metabolism by targeting GLS1, thereby enhancing the sensitivity of liver tumor cells to sorafenib

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