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One possible explanation for the similar effects on weight loss observed with both GIPR agonism and antagonism might be that chronic pharmacological GIPR activation induces functional antagonism in a subset of neurons through receptor desensitization, as seen in adipocytes, isolated pancreatic islets and mouse neuroblastoma Neuro2a cells 36,37
2019 - preclinical mouse model Animal study suggesting MT-2 may affect social behavior through MC4R-oxytocin signaling
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Before and After: Real Skin Stories Charlotte, 42 I was starting to feel like my skin was ageing faster than I was
Rheumatology (Oxford, England)
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