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Induction of autophagy by drug-resistant esophageal cancer cells promotes their survival and recovery following treatment with chemotherapeutics

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This higher threshold is largely due to larger kidneys and livers relative to body size in children versus adults, and hence greater tolerance of paracetamol overdose than adults.[35] Acute paracetamol overdose in children rarely causes illness or death with chronic, supratherapeutic doses being the major cause of toxicity in children

DOI:10.1016/S0736-0266(03)00110-4 D.Pevec, T.Novinscak, L.Brcic, K.Sipos, I.Jukic, M.Staresinic, S.Mise, Impact of pentadecapeptide BPC 157 on muscle healing impaired by systemic corticosteroid application

The key takeaways about IV bolus are that it works instantly, has a higher error rate than infusions, and requires strict timing for safe administration