what is the difference between dulaglutide and semaglutide Comparison of cardiovascular outcomes once‐weekly in adults with type 2 diabetes and established atherosclerotic cardiovascular disease in United States - Tan - 2026 Wegovy vs Trulicity | Wegovy

The new IJO meta-analysis of GLP-1 RAs and body composition (Sawicka-Gutaj et al.) landed today

Im very happy to be here today

Because GLP-1s slow down the stomach, some people feel nauseated or experience constipation or diarrhea when they first start the medication or increase their dose

Clinical trials reveal that 10-15% of participants taking GLP-1 medications like Wegovy or Mounjaro qualify as non-responders, losing less than 5% of their body weight

Ibuprofen does not directly reduce tirzepatide's weight-loss effectiveness, but chronic NSAID use can worsen nausea or gastrointestinal side effects that tirzepatide users already experience