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"We continue to conclude that the benefits of these medications outweigh their risks when they are used according to the FDA approved labeling," spokesperson Chanapa Tantibanchachai said in an email to NPR

We are just now reaching the precipice where 5- and 10-year follow-up data are becoming available for patients taking GLP-1 medications, sayid Muaaz Wajahath, a fourth-year medical student at Michigan State University College of Human Medicine and primary investigator of this study in a press release

Dehydration also worsens other semaglutide side effects like nausea and constipation, creating a cascade that amplifies tiredness

This means it helps your body produce insulin when blood sugar is elevated but does not drive insulin production when blood sugar is normal, reducing hypoglycemia risk

In contrast, the restrictive surgery group (including VSG and gastric banding) showed smaller BMD changes, with even a slight increase in total BMD