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Abstract Type 2 diabetes mellitus is characterised by beta cell failure, which frequently develops in the setting of insulin resistance

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Backed by strong clinical data showing meaningful weight loss and cardiometabolic benefits, this approval expands treatment options for adults with overweight or obesity and could meaningfully impact patient care and access #diabetes #glp1 #Pharmacy To view or add a comment, sign in New #T1D research report out of Denmark: In men with type 1 diabetes (T1D), an intravenous infusion of glucosedependent insulinotropic polypeptide (GIP) did not prevent hypoglycaemia when prandial insulin was given in excess and participants performed postmeal physical activity, but it modestly reduced the peak glucose levels observed after meals compared with the GIP receptor antagonist GIP(3-30)NH2." "'Our findings suggest that supraphysiological levels of GIP do not protect against hypoglycaemia in T1 diabetes, consistent with the similar glucagon levels observed during GIP, the GIPR [GIP receptor] antagonist GIP(3-30)NH2, and placebo infusions.'" Read: GIP Reduces Meal Peaks but Not Hypoglycaemia in T1D #type1diabetes #diabetesresearch #healthcare #health #diabeteshealth To view or add a comment, sign in FDA Approval Update | Obesity Medicine The FDA has approved once-daily oral Wegovy (semaglutide) for chronic weight management in adults with obesity or overweight with at least one weight-related comorbidity, as an adjunct to diet and physical activity

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03 /Clinical data: what the research actually shows Abdulghani et al

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