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BMI, body mass index

Paninfluenza A/B monoclonal nAbs, such as the HA-stem targeting CR9114, have shown protection in lethal heterosubtypic influenza challenge models

Key mechanistic observations from laboratory studies: VEGF upregulation: BPC-157 is thought to upregulate VEGF expression

its blockade increases serotonin release Promotes neurogenesis : TREK-1 knockout mice show increased hippocampal neurogenesis, and PE-22-28 recapitulates this effect pharmacologically within 4 days of treatment Induces synaptogenesis : TREK-1 blockade promotes dendritic growth and synaptic connection formation PE-22-28 inhibits TREK-1 with an IC50 of 0.12 nM, making it approximately 300-500 times more potent than spadin

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