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457 The production of iron-dependent hydroxyl radicals has been associated with muscle necrosis in a mouse model of DMD, and iron deprivation can decrease muscle necrosis and has potential therapeutic benefits

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Since the discovery of FSP1, more and more GPX4-independent ferroptosis pathways have been discovered in various physiological and pathological processes Drugs targeting GPX4-independent ferroptosis pathway may become a new direction for the treatment of diseases

Effects of l-carnitine in patients with hepatic encephalopathy

Zhang P, et al