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In summary, managing abdominal pain in constipation requires a multimodal approach addressing gut motility, visceral hypersensitivity, and neuroimmune dysregulation

10.1172/jci103580 [DOI] [PMC free article] [PubMed] [Google Scholar] Cruz M., Maldonado-Bernal C., Mondragn-Gonzalez R., Sanchez-Barrera R., Wacher N

This study, thus, investigated the impact of storage additives (alkaline E-Sol5 and standard SAGM) and temperatures (+4 C, -4 C, -8 C) on RBC metabolism during 21- and 42-days storage using high-throughput metabolomics

Clinical Update 7/23/2017 Does MSM Help Joints and Muscles

Although, mainly acting as an antioxidant, vitamin E can also exert a pro-oxidant activity