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MECHANISM CATEGORIES RESEARCH CONDITIONS SAFETY Side effects Mild injection-site reactions Transient hunger (mild) Rare water retention Rare mild flushing Known interactions Concurrent rhGH not recommended Insulin / glucose-lowering agents (mild hyperglycemia possible) Contraindications Active malignancy Pituitary tumor Pregnancy/lactation (unstudied) REGULATORY STATUS FDA Not FDA-approved

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They might be caused as a result of structural and chemical changes in the brain

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