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Pevec et al., 2010) and worsening, and immunosuppression (Sikiric et al., 2003)

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*Eligible patients without diabetes lost an average of 21% of their body weight (-48 lbs) in a 72-week clinical trial evaluating 15 mg tirzepatide, when paired with diet and exercise

Additional file 9: Figure S6 (download TIF Volcano plot prepared using the R-library Enhanced Volcano, to represent the differentially expressed genes at p-value cutoff below 0.05, and logFC cutoff value of 0