I too wish they had done more testing of people with autoimmune diseases
Novo Nordisk has filed at least 21 lawsuits nationwide against companies making purported copies of its drugs, accusing them of unlawful mass-producing and advertising "knockoffs." This legal pressure, combined with the FDA's intensified scrutiny, has already led to notable market shifts, such as Hims & Hers abruptly canceling its launch of a GLP-1 pill for weight loss shortly after the FDA's notice and Novo Nordisk's lawsuit
A randomized, double-blind placebo-controlled study of intranasal standardized cinnamon bark extract for seasonal allergic rhinitis
It is estimated that one case of DRESS occurs for every 10,000 drug exposures, particularly anticonvulsants such as carbamazepine.11,12 Among antituberculosis drug users, DRESS occurs in 1.2% of the patients.13 In a retrospective study of 1,253 adult patients receiving antituberculosis drugs between 2006 and 2010, 15 cases (1.2%) of DRESS were observed, in patients with a mean age of 65 years (4874), 53.3% men, with ethambutol being the most used agent (53.5%), followed by rifampicin (26.5%), pyrazinamide (20.0%), streptomycin (13.3%) and isoniazid (6.7%), with a mean latency period of 42 days for developing symptoms and signs of DRESS.14 There is no clear gender predilection among cases of DRESS syndrome
Preclinical evidence is accumulating, and translational research is highly required to increase knowledge on the effect of GLP-1 on reward systems
