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Semaglutide treatment effectively prevented the worsening of diastolic dysfunction, as evidenced by a reduced E/e ratio, and significantly decreased LVEDP by approximately 60% and reduced interstitial fibrosis ( Figure 1D-1E )

Activation of the GHS-R receptor increases both long-term potentiation and the density of dendritic spines of neurons

Wegovy is indicated as an adjunct to a reduced-calorie diet and increased physical activity, not as monotherapy