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(Refer to page 279 for kilogram-to-pound conversions and page 13 for rounding instructions.) Step 2 Calculate the safe dose range (SDR) using a calculator and current safe dose recommendations found in the drug literature or drug handbook for this weight child in mg per kg or mcg per kg

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Suppressing IGF1R reduces DNA damage repair by decreasing ATM phosphorylation, which played a critical role in HR and NHEJ (Turney et al., 2012

Researchers should follow all applicable institutional and regulatory guidelines when working with GH-related peptides