For method 3, magnetically enriched cultures at 90% parasitaemia and 0.12% Hct were incubated with the test compounds for the desired times (drug treatments, 100 nM DHA for 3 h, 300 nM OZ277 for 3 h, 300 nM OZ439 for 6 h, 1 M pyrimethamine for 5 h, and three control conditions, 1 mM DIAM for 5 min, 10 mM DTT for 5 min and DMSO for 6 h)
While effects on some biomarker trajectories were observed, larger trials are needed to evaluate changes in clinical outcomes (Jin et al., 2023
Vekariya KK, Kaur J, Tikoo K (2012) ER signaling imparts chemotherapeutic selectivity to selenium nanoparticles in breast cancer
Chen AS, Batsis JA
Molecular Formula: C172H270N40O54 Molecular Weight: 3762.3 CAT No: ALL-S08812 Keywords: SMILES string - NCC(N[C@@H]([C@@H](C)O)C