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It is a transcription factor that translocates into the nucleus and binds in the promoter regions of detoxifying and antioxidants genes [27]

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Activation of GPR43 by SCFAs triggers intracellular signaling cascades, including increases in intracellular calcium concentration (59, 61) and induces L-cells to secrete endogenous GLP-1 and peptide YY (PYY) (6264)

Safety and efficacy of the SNAP 12-hour acetylcysteine regimen for the treatment of paracetamol overdose