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"The discontinuation rate on the placebo was also quite high (press release says 29%), which makes us think there was something about the study that is odd/unique and will need to get some clarity here," Mizuho healthcare expert Jared Holz wrote

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Fungi like Candida and Aspergillus form drug-resistant biofilms, where extracellular matrices limit antifungal penetration and induce dormant persister cells (Morelli et al., 2021

Accompanying symptoms : Cold intolerance accompanied by fatigue, unexplained weight changes (beyond expected weight loss), hair thinning, dry skin, constipation, or low mood may suggest thyroid dysfunction