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Warm compresses applied for 10-15 minutes three times daily can reduce pain and promote drainage, while over-the-counter ibuprofen (400mg every 6 hours) helps control inflammation

The biological objective is to shift efficacy away from Cmax-limited GLP-1 signaling toward exposure- and residence-timedriven pharmacology, while preserving controlled, functionally relevant GIP co-activation

Pounding on an inflamed gouty joint can prolong the flare

This is challenging when appetite is suppressed, which is why protein shakes formulated for GLP-1 users become valuable tools