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The drug was originally approved for adults with obesity in June 2021

Domestic freezers are not suitable for storing investigational medicinal products

The study protocol and all experimental procedures were approved by the Research Ethics Committee of the National Centre for Radiation Research and Technology (REC-NCRRT), Cairo, Egypt (Permit Number: F/21A/25)

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Most patients notice cold sensitivity peak during the first 48 weeks of treatment, then gradually improve as their body adapts