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So the mechanisms are transferable, but the clinical evidence isn't yet robust

Endocannabinoid system in spinocerebellar Ataxia Type-3 and other Autosomal-Dominant cerebellar ataxias: potential role in pathogenesis and expected relevance as neuroprotective targets

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420 The restrictive functions of the bloodbrain barrier (BBB) block foreign substances from entering the brain, which is the predominant reason for the lack of pathogenesis-targeting therapies