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Bastian SE, Walton PE, Wallace JC, Ballard FJ. Plasma clearance and tissue distribution of labelled insulin-like growth factor-I (IGF-I) and an analogue LR3IGF-I in pregnant rats. J Endocrinol. 1993 Aug;138(2):327-36.doi: 10.1677/joe.0.1380327. PMID: 7693845

At the phylum level, Bacteroidetes was more abundant in the colonic mucosa of the constipated patients, whereas fecal microbiota composition was associated with colonic transit time

Temporary Bloating Though rare, some individuals experience slight bloating or digestive discomfort, which may be related to its immune-modulating and anti-inflammatory properties

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