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The first category consists of prodrugs containing a GSH or GSH-like structure for which a -elimination reaction, catalyzed by GST, releases a cytotoxic compound

Exenatide was originally developed for type 2 diabetes and had to be injected twice a daynot very convenient or cost-effective, so it didnt take off at first

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First, its important to regularly monitor your heart rate, especially when you start taking the medication or when your dose changes

This includes reviewing your weight loss trajectory since surgery, assessing adherence to dietary and lifestyle recommendations, and evaluating for any anatomical or functional complications from the surgery