If youre vegan or mostly plant-based, oral or sublingual B12 is usually enough long term shots are typically for documented deficiency or absorption issues (NIH ODS)
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While it remains to be established if specifically inhibiting LC-NE neurons has a similar effect, these findings suggest that systemic GLP-1R agonists activate presynaptic GLP-1Rs on glutamatergic terminals synapsing onto LC-NE neurons, leading to their activation and suppression of food intake
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Statistical analyses The repeatability of findings was confirmed by performing all experiments a minimum of three times
