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For instance, an 8-week double-blind controlled trial showed that when the subjects used a cream containing 2% L-carnitine daily and combined it with aerobic exercise three times a week, the average local fat thickness decreased by 12%-18%, and the proportion of fatty acid oxidation increased by approximately 15%-20%

The gut microbiota-derived metabolite trimethylamine N-oxide is elevated in Alzheimer's disease

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One 2015 review found patients with a positive lactulose breath test (indicating SIBO) had significantly longer colonic and whole-gut transit times 26