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Die aktuellen Grenzen der Forschung umfassen das Fehlen gro angelegter randomisierter klinischer Studien am Menschen, ein noch unvollstndiges Verstndnis der genauen molekularen Mechanismen und einen Mangel an detaillierten pharmakokinetischen Daten beim Menschen

10.1016/j.biopha.2020.110917 67 LiuB.XuC.WuX.LiuF.DuY.SunJ.et al (2015a)

Earlier shorter trials reported small statistically significant differences but the effect sizes were modest

Wegovy is specifically for people with a body mass index (BMI) of 30 or more, or 27 or more with weight-related health conditions, including prediabetes and high blood pressure

Most people tolerate B12 supplementation well, even at doses significantly higher than the recommended daily amount