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On one hand, its therapeutic efficacy arises from direct inhibition of angiogenesis mediated by VEGFR/PDGFR and tumor cell proliferation driven by c-Kit/FGFR pathways that are potentially active in MMNSTs

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Significantly, L-carnitine can traverse the bloodbrain barrier, positioning it to directly support cerebral energy metabolism and function ( In summary, converging evidence from mechanistic, observational, and interventional research suggests that L-carnitine availability likely contributes to brain tissue growth in preterm infants

Inside the cell, the acetyl group is split off and L-carnitine is released

Challenging clinical cases: What factors should guide your choice of therapy