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doi:10.1001/jamaoto.2014.632

PD is characterized by the progressive loss of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNpc) as well as the presence of -synuclein-containing protein aggregates in the brain, referred to as Lewy bodies (Morris et al., 2024)

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The MHRA has not approved any GLP-1 receptor agonist for use below the labelled doses, and this approach falls outside current prescribing guidelines