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In a Phase 1b trial conducted in China, participants receiving the highest dose of UBT251 demonstrated an average weight loss of 15.1% over 12 weeks, while the placebo group gained 1.5%

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These properties influence the way they interact with surrounding amino acids in polypeptides and proteins, and consequently impact protein 3D structure and properties

References suggest it as a tetrasubstituted variant of the shortest functional GHRH sequence, denoted GRF (1-29)

Lakoumentas JA, Dimitroula TG, Aggeli KI, Harbis Cholesterol levels and the benefit of statins in heart failure