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(2023) 108:e130615

In fact, evidence for its effectiveness is strong enough that, in 2012, the American Academy of Neurology recommended butterbur for preventing migraine

Animal Lifespan Does Not Equal Human Healthspan A lifespan difference in a selected mouse strain can arise from effects on one common cause of death without improving broader health

Additionally, insulin exerts little impact on cardiovascular complications, a key contributor to morbidity and mortality in patients with diabetes (Zheng et al., 2018)