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Although these agents produce substantial and sustained weight reduction, emerging clinical observations suggest that chronic therapy may be accompanied by changes in lean mass trajectory, reduced protein intake, and micronutrient insufficiency

Carnosine is synthesized by bonding of the amino acids -alanine (regulatory function) and L-histidine (biological activity), a reaction catalyzed by carnosine synthase [6,9,23]

[12] Chakraborty S, Roychoudhury S

It also points to a new reality that regulators and the medical establishment have to contend with: a lot of medicine is escaping the traditional boundaries of healthcare