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Low blood pressure (hypotension) is also rare occurring in fewer than 1% of patients and is typically related to dehydration caused by gastrointestinal side effects such as nausea, vomiting, or diarrhea

Novo touted cagrilintide as being well-tolerated, with just 1% of patients who received the drug discontinuing, compared to 0.1% in the placebo arm

Morieri et al., 2025)

Consistent with this, treatment of RYGB patients with exendin (939) increases the fMRI response to images of food in the caudate nucleus, and in the insula in the human brain in response to consuming palatable food [225]

Caregivers giving the suppository to another person often find it easier if the person is lying down