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Metabolic fate and cardiovascular effects of arsenic in rats and rabbits chronically exposed to trivalent and pentavalent arsenic

Their results demonstrated that 4-HNE could form adducts with SOX9 and lead to its ubiquitin-mediated degradation [90]

Teratogenicity studies on rats and rabbits, orally administered 62 mg/kg body weight during gestation, revealed symptoms of intoxication and significant inhibition of ChE in the parent rabbits

Cell 55 , 11891193 (1988)

Overall, the newer small molecule GLP-1 RAs such as danuglipron and orforglipron have shown significant reductions in HbA1c and body weight, comparable to existing GLP-1 RAs