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Pre-existing risk factors common in the diabetes population further compound concern: Older age (reduced intrinsic factor production) Autoimmune conditions (pernicious anaemia, thyroid disease) Previous gastric surgery or gastrointestinal disorders Vegetarian or vegan dietary patterns There is no established link between semaglutide pharmacology and B12 metabolism in the MHRA-approved product information, but the clinical context in which Ozempic is prescribed creates a population where B12 awareness is prudent

Mood and Metabolic Benefits Many of our clients find that B12 injections help with mood regulation, as this vitamin is necessary for synthesizing key neurotransmitters like serotonin and dopamine

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Experimental preclinical doses in rodents range 100 to 500 g/kg/day

24 In a clinically symptomatic patient with specific features of B 12 deficiency, order a B 12 test, see Figure1: B 12 Test Result Review and Process Algorithm for Patients with Risk Factor for B 12 Deficiency* and/or Non- Specific** or Specific Symptom of B 12 Deficiency for more detail