Cherney 1,2,3,5,6 Endocrinology and Metabolism 2021;36(2):256-269
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Although traditional clinical trials, such as the Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus-Thrombolysis in Myocardial Infarction (SAVOR-TIMI) 53 study, demonstrated neutral effects on the progression of DKD in non-selective cohorts, certain subgroup analyses indicated a potential reduction in albuminuria among early-stage DKD patients (110)
Semaglutide is known as a GLP-1 agonist that works with a single receptor
As the use of these drugs becomes ubiquitous, widespread implementation of preoperative anaesthesia clinics should be considered, and excellent communication with the surgical team is essential. The study provides insight into understanding how medical professionals are navigating the intersection of popular drug use and surgical safetyand underscores the need for clear, evidence-based guidance as the use of GLP-1 agonists shows no signs of slowing