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These interactions make DSIP a promising candidate for research on chronic pain and the mechanisms of dependence.DSIP and opioids, 1984, PMID 6548970

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cGMP facilitates smooth muscle relaxation in blood vessels either by enhancing Ca 2+ extrusion or by reducing the sensitivity of the myofilaments to Ca 2+ [102]

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Like all NSAIDs, Aceclofenac is not risk-free