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First-pass metabolism occurs when a compound is absorbed from the gut and passes through the liver, where it can be partially broken down before reaching the rest of the body

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The results indicated that DSIP did not have a significant influence on rotation asymmetry compared to vehicle-treated animals

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10.1016/j.bbrc.2016.10.086 50 GrafH.JngstC.StraubG.DoganS.HoffmannR