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The D-2-naphthylalanine (D-2-Nal) at position 3 a bulky, non-natural amino acid provides critical receptor binding contributions and contributes to selectivity

[DOI] [PubMed] [Google Scholar] 125.Wang J., Li Y

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However, the energy deficit hypothesis fails to fully account for a key clinical feature of PEM: the significant decline in muscle strength (myasthenia) upon the initial contraction after sufficient rest, rather than solely following endurance activities (83)