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How women should prepare for menopause and think about hormone replacement therapy: early planning, symptom awareness, and guidance on HRT [36:45]

The finger pulp or tip and the periungual area are frequently affected with pigmentary macules

124 METTL17 is upregulated in colorectal cancer, and the absence of METTL17 increases the sensitivity of colon cancer cells to ferroptosis, and promotes cell proliferation and the growth of transplanted tumors

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Contact your GP immediately if you experience severe right upper abdominal pain, fever, nausea, vomiting, jaundice (yellowing of skin or eyes), dark urine, or pale stools, as these may indicate gallstone complications requiring urgent assessment