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Genetic studies have revealed that IL1B polymorphisms are associated with increased PD risk, suggesting that individual variability in both TNF- and IL-1 may influence disease susceptibility and early onset [184, 189, 195]

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It is important to remember that the injections are not a complete solution, but rather a tool to aid in achieving weight loss goals

The new label includes references to some of those postmarketing risks, including intestinal obstruction, [and] severe constipation including fecal impaction. Some patients who took Zepbound have filed lawsuits, accusing Eli Lilly of failing to properly warn them that Zepbound could increase their risk of severe gut problems, including bowel obstructions, pancreatitis, and gastroparesis