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Semaglutide may do more than curb cravingsit can alter the sensory enjoyment of food

In subjects with CAD with LDL-C levels well controlled with a statin, the addition of extended release niacin in AIM-HIGH (732) and extended release niacin plus laropiprant (prostaglandin D2 receptor blocker to inhibit flushing) in HPS-2THRIVE (733) failed to reduce cardiovascular outcomes

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The glucagon-like peptide-1 receptor agonist, exendin-4, reduces sexual interaction behaviors in a brain site-specific manner in sexually naive male mice

The same study observed that GLP-1RAs significantly reduced the risk of alcohol abuse by 65% and substance abuse by nearly 50%