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As revealed by KEGG enrichment, the above DEPs were predominantly associated with the glutathione metabolism pathway

By participating in NLRP3 and NF-kB related signalling pathways, empagliflozin, a new hypoglycaemic drug that can improve the prognosis of CVDs, can attenuate ferroptosis, fibrosis, apoptosis, and inflammation in doxorubicin-treated mice and significantly improve cardiac function, thereby opening up a new avenue for the treatment of doxorubicin-related cardiotoxicity [150, 151]

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Interestingly, this stress is resolved at 72 h 5FU (Fig

Epigenetic regulation by quercetin: a comprehensive review focused on its biological mechanisms