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Ultimately, both GL and GA and their metabolites are primarily eliminated via bile and feces, with only a small fraction excreted in urine (Figure 2) ( 3 Core pharmacological mechanisms of glycyrrhizin in the liver GA exerts hepatoprotective effects through multiple pathways and targets, forming a synergistic network that includes anti-inflammatory, antioxidant, liver-protecting, and immunomodulatory actions (Xie et al., 2015) (Table 2

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This makes it much more suitable than sterile water, which is free from living organisms but does not contain any preservatives like 0.9 percent benzyl alcohol that can limit microbial growth in the long run